SKRINING ANTIOKSIDAN DAN ANTIKANKER EKSTRAK ETANOL DAUN KARAMUNTING (RHONOMYRTUS TOMENTOSA L.) SEBAGAI OBAT ALTERNATIF

Abstract

Karamunting (Rhodomyrtus tomentosa (Aiton) is one of the plants used as a traditional medicine that is widely spread throughout Indonesia, especially from Toraja, which has the potential as antioxidants and anticancers with the content of phenolic compounds and flavanoids. This study aims to look at total flavonoids as well as antioxidant activity and toxicity of karamunting leaf extract. Simplisia karamunting leaf research method is extracted by maceration method using ethanol 70%, testing antioxidant activity with ABTS method and toxicity test with BSLT method. The results of the study obtained a total phenolic 3.496% , The acquisition of antioxidant activity of ethanol extract of caramel leaves with ic50 value of 24,451 bpj and the acquisition of toxicity test of ethanol extract of caramel leaves with a value of LC50 of 31.80 bpj against shrimp larvae. Based on the results obtained ethanol extract of caramel leaves has antioxidant activity and has a very strong toxicity effect.